South Africa has one of the highest HIV/AIDS infection rates in the world and most of us are affected by this longstanding pandemic, either in a direct manner or indirectly. Despite widespread awareness and great medical advancements in this field, those infected with HIV/AIDS still face discrimination due to their HIV/AIDS status. It is important to highlight that those infected with HIV/AIDS have the same rights as everyone else, particularly in the context of the workplace where they are highly prone to discrimination due to their HIV/AIDS status. This article will address some of the frequently asked questions on HIV/AIDS in the workplace.